Probable G-protein coupled receptor 12 is a protein that in humans is encoded by the GPR12 gene.

The gene product of GPR12 is an orphan receptor, meaning that its endogenous ligand is currently unknown. Gene disruption of GPR12 in mice results in dyslipidemia and obesity.

Ligands

Inverse agonists
  • Cannabidiol

Evolution

Paralogues

Source:

  • GPR6
  • GPR3
  • S1PR5
  • CNR1
  • CNR2
  • MC4R
  • S1PR1
  • MC3R
  • MC2R
  • S1PR2
  • MC1R
  • S1PR3
  • LPAR2
  • MC5R
  • LPAR1
  • S1PR4
  • LPAR3
  • GPR119

References

Further reading


GPR System Gallery The European GPR Association

GPR System Gallery The European GPR Association

GPr_29.JPG

TWELVE12 GPR, Inc.

Ltrade GPR121