Furoxan (1,2,5-oxadiazole 2-oxide) is a heterocycle of the isoxazole family and an amine oxide derivative of furazan. It is a nitric oxide donor. As such, furoxan and its derivatives, such as ipramidil, are being actively studied as potential new drugs and insensitive high density explosives (4,4’-dinitro-3,3’-diazenofuroxan).
Furoxanes can be formed by dimerization of nitrile oxides.
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